Bayer AG was founded in Barmen, Germany in 1863 was a dyestuffs factory. Their first product was aspirin and is still the best known.
In 1898 Bayer trademarked the name heroin for the drub diacetylmorphine and sold it as a cough medicine and a substitute for morphine until 1910.
This was a 1920 ad in The Sutton Register.
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